@article{Bhardwaj_A._B._Gupta_2018, title={ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY: A REVOLUTIONIZED LC TECHNIQUE}, volume={2}, url={https://ijdra.com/index.php/journal/article/view/146}, DOI={10.22270/ijdra.v2i3.146}, abstractNote={<p>High Performance Liquid Chromatography (HPLC) is a major technique for qualitative and quantitative drug analysis. More than 90% of drugs prescribed in official pharmacopoeias are being analyzed HPLC. HPLC analyzes the drug content in a sample with high degree of accuracy and precision. Due to the stringent regulatory requirements the number of samples for drug content analysis has been increased significantly. Therefore, pharmaceutical industries need a fast, accurate and affordable method for drug content analysis. Here, Ultra Performance Liquid Chromatography (U-PLC) offers an advancement of HPLC which is based on the principal of use of stationary phase consisting of particles less than 2μm. By using smaller particles; speed and peak capacity can be extended to new limits and the sample can be analyzes in a shorter period of time. It provides good resolution even for congeneric compounds. The present review discusses the various aspects of UPLC in pharmaceutical analysis.</p&gt;}, number={3}, journal={International Journal of Drug Regulatory Affairs}, author={Bhardwaj, Shalini and A., Vandana and B., Vijay and Gupta, Manish K.}, year={2018}, month={Feb.}, pages={83-87} }