FORMULATION AND DEVELOPMENT OF KETOPROFEN BILAYER TABLETS

  • D R Nagesh Institute of Pharmacy, Shri JJT University Jhunjhunu (Raj) India.
  • Rakesh Kumar Jat Institute of Pharmacy, Shri JJT University Jhunjhunu (Raj) India.
  • Syed Mansoor Ahmed Sree Siddaganga College of Pharmacy, Tumkuru, Karnataka, India.

Abstract

Aim of present research work was formulation and development of bilayer tablets of Ketoprofen to reduce the side
effects of Ketoprofen and to improve the therapeutic benefits and patients’ compliance to treatment. Bi-layer tablets
of Ketoprofen were prepared by direct compression technique using excipients like MCC, superdisintegrant,
aspartame, colour agent were mixed properly shifted from sieve no 40. Before compression; add talc magnesium
stearate mixed it well. Formulations with optimal properties have been selected to obtain bi-layer tablets of adequate
quality. The in vitro dissolution study of the prepared bilayer tablets showed a controlled release of active drugs over
a period of 24 hours.
 

Keywords: Bilayer Tablets, Ketoprofen, Superdisintegrant.

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Author Biographies

D R Nagesh, Institute of Pharmacy, Shri JJT University Jhunjhunu (Raj) India.

institute of Pharmacy, Shri JJT University Jhunjhunu (Raj) India.

Rakesh Kumar Jat, Institute of Pharmacy, Shri JJT University Jhunjhunu (Raj) India.

Institute of Pharmacy, Shri JJT University Jhunjhunu (Raj) India.

Syed Mansoor Ahmed, Sree Siddaganga College of Pharmacy, Tumkuru, Karnataka, India.

Sree Siddaganga College of Pharmacy, Tumkuru, Karnataka, India.

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How to Cite
Nagesh, D. R., R. K. Jat, and S. M. Ahmed. “FORMULATION AND DEVELOPMENT OF KETOPROFEN BILAYER TABLETS”. International Journal of Drug Regulatory Affairs, Vol. 5, no. 4, Dec. 2017, pp. 26-32, doi:10.22270/ijdra.v5i4.207.